A number of prominent front-end developers delivered helpful talks at this year's Fronteers 2011 conference in Amsterdam.

In this (provocatively titled) video, Aral Balkan offers a series of radical suggestions on how UI considerations -- or, better, the primacy of user experience -- will encourage a new level of device integration that will tend to erase the distinction between native and web apps. 

You can also view the slides and read the transcript.